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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRI All Species: 26.36
Human Site: S117 Identified Species: 52.73
UniProt: P30626 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30626 NP_003121.1 198 21676 S117 I S F D T D R S G T V D P Q E
Chimpanzee Pan troglodytes XP_001164377 195 21319 S111 G W R Q H F I S F D T D R S G
Rhesus Macaque Macaca mulatta XP_001104452 198 21685 S117 I S F D T D R S G T V D P Q E
Dog Lupus familis XP_532452 198 21674 S117 I S F D S D R S G T V D P Q E
Cat Felis silvestris
Mouse Mus musculus Q6P069 198 21609 S117 I S F D S D R S G T V D P Q E
Rat Rattus norvegicus Q641Z8 283 29994 I200 D R D H S G S I S S T E L Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509134 180 20521 S99 M S F D S D R S G T V E P Q E
Chicken Gallus gallus NP_001074334 198 21861 S117 V N F D S D R S G A V D R Q E
Frog Xenopus laevis Q5PQ53 283 30514 I200 D R D R S G S I N Q G E L H Q
Zebra Danio Brachydanio rerio Q6DC93 270 29406 I187 D R D R S G S I N T N E M H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783992 192 21485 S111 M T Y D R D R S G Q I E P H E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W4L0 335 35283 D251 K D R S G R I D T N E L R D A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.9 99.4 98.9 N.A. 95.9 31.4 N.A. 75.7 83.8 30.3 31.8 N.A. N.A. N.A. N.A. 60.6
Protein Similarity: 100 97.4 99.4 99.4 N.A. 98.4 42.7 N.A. 81.8 92.4 44.5 44 N.A. N.A. N.A. N.A. 72.2
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 6.6 N.A. 80 66.6 0 6.6 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 33.3 N.A. 100 86.6 20 26.6 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 22.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 34.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 9 25 59 0 59 0 9 0 9 0 50 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 42 0 0 59 % E
% Phe: 0 0 50 0 0 9 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 9 25 0 0 59 0 9 0 0 0 9 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 25 0 % H
% Ile: 34 0 0 0 0 0 17 25 0 0 9 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 9 17 0 0 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 17 9 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 17 0 0 0 59 25 % Q
% Arg: 0 25 17 17 9 9 59 0 0 0 0 0 25 0 0 % R
% Ser: 0 42 0 9 59 0 25 67 9 9 0 0 0 9 0 % S
% Thr: 0 9 0 0 17 0 0 0 9 50 17 0 0 0 0 % T
% Val: 9 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _